Welcome to the UCSC Genome Browser website. This site contains the reference sequence and working draft assemblies for a large collection of genomes. It also provides portals to ENCODE data at UCSC (2003 to 2012) and to the Neandertal project. Download or purchase the Genome Browser source code, or the Genome Browser in a Box (GBiB) at our online store.

WARNING: This is a test server. Data and tools on this website are under construction, have not been reviewed for quality, and are subject to change at any time. For high-quality, reviewed annotations on our production server, visit http://genome.ucsc.edu.

WARNING: This is our preview site. This website is a weekly mirror of our internal development server for public access. Data and tools on this site are under construction, have not been reviewed for quality, and are subject to change at any time. We provide this site for early access, with the warning that it is less available and stable than our public site. For high-quality, reviewed annotations on our production server, visit http://genome.ucsc.edu.

We encourage you to explore these sequences with our tools. The Genome Browser zooms and scrolls over chromosomes, showing the work of annotators worldwide. The Gene Sorter shows expression, homology and other information on groups of genes that can be related in many ways. Blat quickly maps your sequence to the genome. The Table Browser provides convenient access to the underlying database. VisiGene lets you browse through a large collection of in situ mouse and frog images to examine expression patterns. Genome Graphs allows you to upload and display genome-wide data sets.

The UCSC Genome Browser is developed and maintained by the Genome Bioinformatics Group, a cross-departmental team within the UC Santa Cruz Genomics Institute and the Center for Biomolecular Science and Engineering (CBSE) at the University of California Santa Cruz (UCSC). If you have feedback or questions concerning the tools or data on this website, feel free to contact us on our public mailing list.

The Genome Browser project team relies on public funding to support our work. Donations are welcome -- we have many more ideas than our funding supports! If you have ideas, drop a comment in our suggestion box.

To receive announcements of new genome assembly releases, new software features, updates and training seminars by email, subscribe to the genome-announce mailing list. Please see our blog for posts about Genome Browser tools, features, projects and more.

29 October 2014 - Genome Browser in a Box (GBiB)

Sometimes you just want to keep your genomics data to yourself. Have you ever hesitated when uploading your data set into the UCSC Genome Browser? If so, you'll be happy to know that we have created a stand-alone personal version: Genome Browser in a Box (GBiB). If you have sensitive genomics data that you would like to view securely on your own laptop in the context of the UCSC Genome Browser, GBiB is for you.

GBiB is an easy-to-install personal copy of the Genome Browser that comes preloaded with the most popular annotation tracks for human. It is highly configurable — you can access or download other annotation tracks of interest, or view any of the other 90+ organisms featured in the public Genome Browser. GBiB runs inside of Oracle's free VirtualBox virtual machine. It has the same core functionality as the UCSC Genome Browser, but keeps your data private and local to your own computer.

GBiB is free for non-commercial use by non-profit organizations, academic institutions, and for personal use. Commercial use requires purchase of a license with setup fee and annual payment. Download or purchase GBiB in our secure online store.

You can read more about GBiB on our blog, or in the help doc.

We are pleased to announce the release of four tracks derived from NCBI dbSNP Build 141 data, available on the two most recent human assemblies GRCh37/hg19 and GRCh38/hg38. The new tracks contain additional annotation data not included in previous dbSNP tracks, with corresponding coloring and filtering options in the Genome Browser.

There are three SNP tracks available for the GRCh37/hg19 assembly. One is a track containing all mappings of reference SNPs to the human assembly, labeled "All SNPs (141)". The other two tracks are subsets of this track and show interesting and easily defined subsets of dbSNP:

• Common SNPs (141): uniquely mapped variants that appear in at least 1% of the population or are 100% non-reference
• Flagged SNPs (141): uniquely mapped variants, excluding Common SNPs, that have been flagged by dbSNP as "clinically associated"

Unlike previous dbSNP releases for GRCh37/hg19, Build 141 does not include mappings to alternate haplotype sequences. In addition, variants that map to multiple genomic locations (e.g. to different chromosomes, or more than one position on the same chromosome) have been removed.

This release also marks the first set of dbSNP data available for the newest human assembly, GRCh38/hg38. In addition to the three tracks described for hg19, there is one additional track available for hg38:

• Mult. SNPs (141): variants that have been mapped to more than one genomic location

By default, only the Common SNPs (141) are visible; other tracks must be made visible using the track controls. You will find the other SNPs (141) tracks on both of GRCh37/hg19 and GRCh38/hg38 browsers in the "Variation" group.

The tracks were produced at UCSC by Angie Hinrichs and Matthew Speir. We'd like to thank the dbSNP group at NCBI for providing access to these data.

We're excited to introduce a new blog that will feature posts by Genome Browser staff and guests. On the blog we'll be publishing in-depth information about UCSC Genome Browser features, tools, projects and related topics that we hope people will find both useful and interesting. We just published our inaugural post written by Jim Kent, the UCSC Genome Browser Architect and PI, on the 2014 Ebola Epidemic.

If you have a suggestion for a blog post topic, please let us know via our suggestion box.

30 September 2014 - Genome Browser for the Ebola Virus Now Available: We are excited to announce the release of a Genome Browser for the June 2014 assembly of Ebola Virus (Sierra Leone 2014 (G3683/KM034562.1), UCSC version eboVir3). Read more.

23 September 2014 - Ensembl Regulatory Build Now Available in the Genome Browser: We are pleased to announce that data from the Ensembl Regulatory Build is now available in the UCSC Genome Browser as a public track hub for both hg19 and hg38. Read more.

The Genome Browser software, sequence and annotation data are freely available for use with these conditions. A license is required for commercial use of the software. For assistance with questions or problems regarding the UCSC Genome Browser software, database, genome assemblies, or release cycles, click here.

Program-driven use of this software is limited to a maximum of one hit every 15 seconds and no more than 5,000 hits per day.

The UCSC Genome Browser was created by the Genome Bioinformatics Group of UC Santa Cruz. Software Copyright (c) The Regents of the University of California. All rights reserved.